As reported by World Health Organization, Cardiovascular Diseases (CVDs) represent today the leading cause of death worldwide. In many cases, e.g. heart failure, prevention is fundamental, but it is made difficult by technological limits along with the unavailability of reliable and easy-to-use diagnostic tools, particularly at domiciliary level.

This line of research focuses on the design and development of noninvasive devices for the prevention and early diagnosis of CVDs.

Development includes both the phase of the design of the hardware and the phase of signal processing at software level. Our interest mainly concerns the design of innovative techniques for the acquisition and analysis of electrocardiographic signal and heart sounds.

Our long-term goal is to set up a telemedicine system for the home monitoring of at-risk patients based on our developed devices.


  • Marco Knaflitz (Full Professor)
  • Noemi Giordano (Ph.D. Student)

  • Recent publications:

  • A novel method for measuring the timing of heart sound components through digital phonocardiography
      N. Giordano and M. Knaflitz
  • Automated Assessment of the Quality of Phonocardographic Recordings through Signal-to-Noise Ratio for Home Monitoring Applications
      N. Giordano, S. Rosati, and M. Knaflitz
  • A Method for the Estimation of the Timing of Heart Sound Components Through Blind Source Separation in Multi-Source Phonocardiography
      N. Giordano and M. Knaflitz
      2020 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
  • Multi-source signal processing in phonocardiography: comparison among signal selection and signal enhancement techniques
      N. Giordano and M. Knaflitz
      2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)