Research – BIOLAB@PoliTO

Research areas:

Analysis of the Physicians’ Workload in a Reference Center for the Treatment of Thrombotic and Bleeding Disorders

Brief Description: There is a strict relationship between workload, quality of care and clinical outcomes. Consequently, the quantification and reduction of physician’s workload is an issue worth of being effectively faced and solved. Given the high complexity ...read more...

Carotid-Femoral Pulse Wave Velocity analysis from Laser Doppler Vibrometer Signals

Brief Description: Many studies have shown that the stiffness of elastic arteries like the aorta independently predicts cardiovascular risk. the gold standard for the arterial stiffness assessment in daily practice is the carotid-femoral pulse wave velocity (PWV). This inde ...read more...

Clinical Process Modelling

Brief Description: By the term “process” we mean a series of activities that have a start and a final result. During the process actors interact among them to perform actions and to reach the result. Actors may be humans or machines. Behind the process there is a system ...read more...

Dermatological image analysis

Brief Description: Dermatology is the branch of medicine dealing with the skin and it is a specialty with both medical and surgical aspects. Dermatological imaging plays a key role in the clinical evaluation of skin lesions. The appearance, morphology, shape, and distributi ...read more...

Design of a MIMU-based wearable devices network

Brief Description: The world is becoming more and more health-conscious. Society, health policy, and patients’ needs are all changing dramatically. The challenges society is currently facing are related to the increase in the aging population, changes in lifestyle, the need ...read more...

Design of a NIRS wearable device

Design of sensing devices for telemedicine applications in cardiology

Brief Description: As reported by World Health Organization, Cardiovascular Diseases (CVDs) represent today the leading cause of death worldwide. In many cases, e.g. heart failure, prevention is fundamental, but it is made difficult by technological limits along ...read more...

Digital pathology image analysis

Brief Description: The analysis of histological slides is fundamental for cancer diagnosis and grading, typically performed by an expert pathologist, and this process is becoming more and more complex due to the rise in cancer incidence and patient-specific treatment option ...read more...

EEG signal decomposition in sleep analysis

Brief Description: Sleep quality can be compromised by sleep-related disorders such as sleep apnea, depression, insomnia or narcolepsy and the chronic restriction has negative consequences both on the health of individual and on public security. The development of new techn ...read more...

Effects of bilateral sub-thalamic nucleus deep brain stimulation on gait in patients affected by Parkinson's disease

Brief Description: Gait deficits are the principal source of disability and loss of independence in patients affected by Parkinson's Disease (PD). Tremor, bradykinesia, and rigidity are usually responsive to medical treatment with levodopa (L-dopa) and to bilateral ...read more...

Fluorescence microscopy image analysis

Brief Description: Fluorescence microscopy is a widely used tool for monitoring cellular physiology. The absorption and subsequent re-radiation of light by organic and inorganic specimens is typically the result of well-established physical phenomena described as fluorescen ...read more...

Identification of Active Bone Marrow from CT images

Brief Description: A crucial point in radiotherapy is to correctly identify bone marrow (BM) and implement strategies able to selectively spare it, since the radiation dose received by this structure is a predictive factor for hematologic toxicity occurrence. ...read more...

Innovative techniques for ultrasound beamforming

Brief Description: Ultrasound imaging can be effective for analysing pathological and normal tissues, by studying both the structure and texture in B-mode images. The output B-mode image is influenced by several technical aspects during acquisition, such as the probe freque ...read more...

Machine learning for muscle activation patterns identification during cyclical movements

Brief Description: Cyclical movements are characterized by different muscle activation patterns (onset-offset timings). To interpret correctly the electromyographic (EMG) data, it is important to group cycles sharing similar EMG activation patterns. We developed a method ...read more...

Medical Device Software

Brief Description: Medical device software are playing an increasingly important role in healthcare. Designing and developing high quality, safe, effective, usable and innovative medical device software is a difficult task, which comprises many activities. ...read more...

Multi-modal CT/PET analysis for neuroendocrine tumors

Brief Description: Neuroendocrine neoplasms (NENs) are a heterogeneous group of malignancies which arise from neuroendocrine cells and are divided into well-differentiated neuroendocrine tumors (NETs) and poorly differentiated neuroendocrine carcinomas (NECs). Currently, 18 ...read more...

Multisensory integration in balance control

Brief Description: Balance control is a complex motor skill, which involves the integration of many types of sensory information (sight, vestibular system and proprioception). Postural control can be modified by sensory input alterations consequent to a pathology: vision ...read more...

Muscle synergy assessment during cyclic and non-cyclic movements

Brief Description: Motor tasks are achieved by activating an appropriate set of muscles depending on the task constraints of a specific movement. The central nervous system (CNS) plays the main role in motor control since it activates each muscle choosing ...read more...

Nerve stimulation in tetraplegic patients

Brief Description: The social cost of spinal cord injuries (SCIs) causing high tetraplegia (C1 to C4) can be considered very high, due to the increasing general life expectancy and the quality of medical care. These traumatic events have devastating consequences from ...read more...

Non-invasive analysis of actinic keratosis using Near-Infrared Spectroscopy

Brief Description: Non-melanoma skin cancers (NMSC) are the most common human cancers, particularly in the Caucasian population. The possible evolution of actinic keratoses (AKs) into invasive squamous cell carcinomas (SCC) makes their treatment and monitoring essential. A ...read more...

Non-invasive vascular quantification using ultrasound imaging and biomedical optical imaging

Brief Description: Blood vessels are the only system to provide nutrients and oxygen to every part of the body. Many diseases can have significant effects on blood vessel formation, so the vascular network can be a cue to assess malicious tumor and ischemic tissues. Various ...read more...

Quantitative analysis of ECG patterns in Brugada Syndrome

Brief Description: In recent years, Brugada syndrome has increasingly assumed greater importance in the clinical setting given the high number of young people between 30 and 40 years of age who have died due to it. The cause of this syndrome is not entirely clear but is at ...read more...

Radio-pathomics for personalized chemotherapy treatment

Brief Description: In the last decade, multi‐omics has gained increasing importance in the biomedical field. Indeed, incorporating different biological layers of information such as radiological and pathological images and genetic and clinical data has become crucial ...read more...

Radiomics and AI for CAD Systems development

Brief Description: Radiomics is defined as “process designed to extract a large number of quantitative features from digital images”. Its final aim is to extract hidden information from images that can be useful to develop Computer-Aided Diagnosis (CAD) systems and decision ...read more...

Statistical gait analysis

Brief Description: Gait analysis is widely used in clinics to study walking abnormalities for surgery planning, definition of therapeutic and rehabilitation protocols, and objective evaluation of clinical outcomes. Among the principal applications of clinical gait ...read more...

Synthetic image generation using Generative Adversarial Networks (GANs)

Brief Description: In the deep learning era, having access to a large quantity of data is fundamental to build systems with the desired performances and reliability. The medical field is not an exception. Moreover, the added challenges of dealing with sensitive data, follow ...read more...

The impact of ultrasound beamforming techniques on image processing algorithms

Ultrasound B-mode image segmentation and radiomics

Brief Description: Ultrasound imaging is widely used in medicine thanks to its many advantages: this versatile imaging technique does not use ionizing radiation, is inexpensive, allows real-time imaging, and is portable, allowing for crucial point-of-care applications. On t ...read more...